Publications

  1. Lockhart, J.N.; Beezer, D.B.; Stevens, D.M.; Spears, B.R.; Harth, E.”One-pot polyglycidol via liposome master templates for dual drug delivery.” Journal of Controlled Release, 2016, DOI: 10.1016/j.jconrel.2016.07.013                                                                                                                                                                                                                                                                                 Jake TOC CR.jpg
  2. Spears, B.R.; Marin, M.A.; Chaker, A.N.; Lampley, M.W.; Harth, E.”Precise Microscale Polymeric Networks through Piezoelectronic Inkjet Printing.” ACS Biomaterials Science and Engineering, 2016, DOI: 10.1021/acsbiomaterials.6b00175                                                                                                                                                                                                                       Ben Toc printing.jpg
  3. Beezer, D.B.; Harth, E.”Post-polymerization modification of branched polyglycidol with N-Hydroxy phthalimide to give ratio-controlled amino-oxy functionalized species.” Journal of Polymer Science Part A: Polymer Chemistry, 2016, DOI: 10.1002/pola.28168                                                                                                                                                                                                           Dain TOC
  4. Spears, B.R.; Marin, M.A.; Montenegro-Burke, J.R.; Evans, B.C.; McLean, J.; Harth, E.”Aqueous Epoxide Ring-Opening Polymerization (AEROP): Green Synthesis of Polyglycidol with Ultralow Branching.” Macromolecules, 2016, 49 (6), 2011-2027.                                                                                                                                                                                                                                    TOC green revision
  5. Gilmore, K.A.; Lampley, M.W.; Boyer, C.; Harth, E. “Matrices for combined delivery of proteins and synthetic molecules.” Advanced Drug Delivery Reviews, 2016, 98,77-85 http://dx.doi.org/10.1016/j.addr.2015.11.018                                                                                                                                                                                                                                                                                     TOC review new
  6. Harth, E.; Nicolas J.; Book Chapter 9: NMP-derived Materials for Biomedical Applications, 2015, 383-405 in RSC Polymer Chemistry Series: Nitroxide Mediated Polymerization: From Fundamentals to Applications in Materials Science, Editor: Didier Gigmes; http://pubs.rsc.org/en/content/ebook/978-1-78262-061-7#!divbookcontent                                                                                                                                                                                                                                                                                                                                                                            book
  7. Lockhart, J.N.; Stevens, D.M.; Beezer, D.B.; Karvitz, A.; Harth, E. “Dual drug delivery of tamoxifen and quercetin: Regulated metabolism for anticancer treatment with nanosponges.” Journal of Controlled Release, 2015, 751-757. http://dx.doi.org/10.1016/j.jconrel.2015.08.052TOC JCR
  8. Lambert. W.S.; Carlson, B.J.; van der Ende, A.E.; Shih, G.; Dobish, J.N.; Calkins, D.J.; Harth, E. ” Nanosponge-Mediated Drug Delivery Lowers Intraocular Pressure.” Translational Vision Science and Technology, 2015, Vol.4, No 1, Article 1. http://tvstjournal.org/doi/full/10.1167/tvst.4.1.1eye
  9. Stevens, D.M.; Rahalkar, A.; Spears, B.; Gilmore, K.; Douglas, E.; Muthukumar, M.; Harth, E., “Semibranched polyglycidols as “fillers” in polycarbonate hydrogels to tune hydrophobic drug release.” Polymer Chemistry, 2015, DOI:10.1039/c4py00986jTOC Daid Hydrogel
  10. De la Croix Ndong, J.; Stevens, D.M.; Vignaux, G.; Uppuganti, S.; Perrien, D.; Yang, X.; Nyman, J.S.; Harth, E.; Elefteriou, F., “Combined MEK inhibition and BMP2 treatment promotes osteoblast differentiation and bone healing in Nf1oSX mice.” Journal of Bone and Mineral Research, 2015, Vol.30, 55-63 http://onlinelibrary.wiley.com/doi/10.1002/jbmr.2316/abstractdoc1
  11. Holder, K.M.; Spears, B.R.; Huff, M.E.; Priolo, A.; Harth, E.; Grunlan, J. C. “Stretchable gas barrier achieved with partially hydrogen-bonded multilayer nanocoating.” Macromolecular Rapid Communications, 2014, 35(10), 960-964.  [article]doc2
  12. Stevens, D.M.; Gilmore, K.A.; Harth, E.”An assessment of nanosponges for intravenous and oral drug delivery of BCS class IV drugs: Drug delivery kinetics and solubilization.” Polymer Chemistry, 2014, 5, 3551-3554. (Paper of the Week, Polymer  Chemistry, RSC)  [article] doc3
  13. Hariri, G.; Edwards, A. D.;  Merrill, T.B.; Greenbaum, J.; van der Ende, A.E.; Harth, E.“Sequential targeted delivery of paclitaxel and camptothecin using a cross-linked “nanosponge” network for lung cancer chemotherapy.” Molecular Pharmaceutics, 2014, 11(1), 265-275.
    Sequentail Chemotherapy of Targeted Nanosponges
  14. Grove, K.; Dobish, J.; Harth, E.; Ingram, M.-C.; Galloway, R.L.; Mawn, L. “Trans-meningeal drug delivery to optic nerve ganglion cell axons using a nanoparticle drug delivery system.” Experimental Eye Research, 2014, 118, 42-45, Short Communication, DOI:10.1016/j.exer.2013.10.016; http://www.sciencedirect.com/science/journal/00144835/118
  15. Sapparapu, G.; Sims, A.L.; Aiyegbo, M.S.;  Shaikh, F.Y.; Harth, E.; Crowe, J.E. “Intracellular neutralization of a virus using a cell-penetrating molecular transporter.” Nanomedicine, 2014, Vol 9, No.11, 1613-1624, DOI:10.2217/nnm.13.139; http://www.futuremedicine.com/toc/nnm/9/11.
    Treatment of Viral Infections
  16. Adkins C.T.; Dobish, J.N.; Brown, S.; Harth,E. “Water-soluble semiconducting nanoparticles for Imaging.” ACS Macro Lett., 2013, 2 (8), 710-714. DOI: 10.1021/mz400370f
    ACS Macro 2013
  17. Spears, B.R.; Waksal, McQuade, C.; Lanier,L.; and Harth, E.“Controlled branching of polyglycidol and formation of protein–glycidol bioconjugates via a graft-from approach with “PEG-like” arms.” Chemical Communication, 2013, 49, 2394-2396.
    ChemComm Cover       Chem. Commun. 2013
  18. Stevens, D.; Watson, H.; LeBlanc, M.A.; Wang, R.; Chou, J.; Bauer, W.; Harth, E.“Practical polymerization of functionalized lactones and carbonates with Sn(OTf)2 in metal catalysed ring-opening polymerization methods.” Polymer Chemistry, 2013, 4, 2470-2474.
    Polym. Chem. 2013
  19. Stevens, D.M.; Tempelaar, S.; Dove, A.; Harth, E. “Nanosponge formation from organocatalytically synthesized poly(carbonate) copolymers.” ACS MacroLetters, 2012, 1(7), 915-918.
    ACS Macro Letters
  20. Dobish, J.N.; Hamilton, S.K.; Harth, E. “Synthesis of low-temperature cross-linker and utilization.” Polymer Chemistry, 2012, 3(4), 857-860.
    illustration
  21. Adkins, C.T.; Dobish, J.N.; Brown, C.S.; Mayrsohn, B.; Hamilton, S.K.; Udoji, F.; Radford, K.; Yankeelov, T.; Gore, J.C.; Harth, e. “High relaxivity MRI imaging reagents from bimodal star polymers.” Polym. Chem., 2012, 3, 390-398. DOI: 10.1039/C1PY00474C, Paper
    illustration
  22. Hamilton, S.K.; Sims, A.L.; Donovan, J.; Harth, E. “Non-viral siRNA delivery vectors: Dendritic molecular transporter and molecular transporter nanovectors for target gene silencing.” Polymer Chemistry, 2011, 2(2), 441-446 (Emerging Investigator issue)
    pub_Poly Chem RSC
  23. Van der Ende, Alice E.; Harrell, J.; Sathiyakumar, V.; Mischievitz, M.; Katz, J.; Adcock, K.; Harth E.* ““Click” Reactions: Novel Chemistries for the Synthesis of Polyester Nanoparticles.” Macromolecules, 2010, 43 (13), 5665-5671.†
    † top seventh most read article in June 2010 (listed are top twenty)
    macromolecules
  24. Passarella, R. J.; Spratt, D.E; van der Ende, A.E.; Phillips, J.G.; Wu, H.; Sathiyakumar, V.; Zhou, L.; Hallahan, D.E.; Harth, E.; Diaz, R. “Targeted delivery systems with a sustained release.” Cancer Research, 2010, 70, 4550-4559. Highlighted by the National Cancer Institute (NCI) Alliance for Nanotechnology in Cancer website, July 14, 2010. http://nano.cancer.gov/action/news/2010/jul/nanotech_news_2010-07-14b.asp nanoparticle-news
  25. Van der Ende, A.; Sathiyakumar, V.; Diaz, R.; Hallahan, D.E.; Harth, E. “Linear release nanoparticle devices for advanced targeted cancer therapies with increased efficacy.” Polymer Chemistry, 2010, 1, 93-96.
  26. Adkins, C.T.; Muchalski, H.; Harth, E. “Nanoparticles with individual site-isolated semiconducting polymers from intramolecular chain collapse processes.” Macromolecules, 2009, 42 (15), 5786-5792.
  27. Hamilton, S.K.; Harth, E. “Molecular Dendritic Transporter Nanoparticle Vectors Provide Efficient Intracellualar Delivery of Peptides.” ACS Nano, 2009, 3 (2), 402-410.
  28. Van der Ende, A.; Croce, T.; Hamilton, K.; Sathiyakumar, V.; Harth, E. “Tailored Polyester Nanoparticles: Post-Modification with Dendritic Transporter and Targeting Units via Reductive Amination and Thiol-ene Chemistry.” Soft Matter2009, 5, 1417-1425.
  29. Hamilton, S.K.; Ikizler, M.R.; Wallen, C; Wright, P.F.; Harth, E. “Effective Delivery of IgG antibodies into infected cells via IgGMT conjugate.” Molecular Biosystems, 2008, 4, 1209-1211. (Article highlighted in Chemical Biology, RSC)
  30. Van der Ende, A.E.; Kravitz, E.J.; Harth E. “Approach to Formation of Multifunctional Polyester Particles in Controlled Nanoscopic Dimensions.” Journal of the American Chemical Society, 2008, 130, 8706-8713. PDF
  31. Adkins, C.T.; Harth, E. “Synthesis of Star Polymer Architectures with Site-Isolated Chomophore Cores.” Macromolecules, 2008, 41(10); 3472-3480. PDF
  32. Somarajan, S.; Hasan, S.A.; Adkins, C.T.; Harth, E.; Dickerson, J.H. “Controlled Electrophoretic Deposition of Uniquely Nanostructured Star Polymer Films.” Journal of Physical Chemistry B, 2008, 112(1), 23-28.
  33. Huang, K.; Croce, T.A.; Hamilton, S.K.; Adkins, C.T.; Evans, B.L. III.; Harth, E. “”Effective Drug Therapies from Functional, Macromolecular Building Blocks with a Biomimetic Design.” Macromol. Symp. 2007, 255, 20-23.
  34. Croce, T., Hamilton, S.K., Chen, M.L., Muchalski, H., Harth, E., “Alternative o-chinodimethane crosslinking precursors for intramolecular chain collapse nanoparticles.” Macromolecules, 2007, 40(17),6028-6031.
  35. Huang, K., Voss, B., E., Kumar, D., Hamm, H. E., Harth, E., “Highly targeted intracellular delivery: Tailored dendritic molecular transporter.” Bioconjugate Chemistry, 2007, 18, 403-409.
  36. Harth, E., Croce, T.A., “Carving out niches for nanostructures: Implementation and interplay of building blocks, methods and tools.” Australian Journal of Chemistry, 2006, 59, 525-533.
  37. Chung, I.D.; Britt, P.; Xie, D.; Harth, E.; Mays, J.,” Synthesis of amino acid-based polymers viaatom transfer radical polymerization in aqueous media at ambient temperature.” Chemical Communication, 2005, 1046.
  38. Drockenmuller, E.; Li, L.Y.T.; Ryu, D. Y.; Harth, E.; Russell, T.P.; Kim, H.C.; Hawker, C.J. “Covalent Stabilization of Nanostructures: Robust Block Copolymer Templates from Novel Thermoactive Systems.” Journal of Polymer Science Part A – Polymer Chemistry. 2005, 43, 1028.
  39. Götz, H.; Harth, E.; Schiller, S.M.; Frank, C. W.; Knoll, W.; Hawker, C.J., “Synthesis of lipo-glycopolymer amphiphiles by nitroxide-mediated living free-radical polymerization” Journal of Polymer Science Part A-Polymer Chemistry, 2002, 40, 3379.
  40. Harth, E.; Van Horn, B.; Lee, V.Y.; Germack, D.S.; Gonzales, C.P.; Miller, R.D.; Hawker, C.J. “A facile approach to architecturally defined nanoparticles via intramolecular chain collapse.” Journal of the American Chemical Society 2002, 124, 8653.
  41. Blomberg, S.; Ostberg, S.; Harth, E.; Bosman, A.W.; Van Horn, B.; Hawker, C.J,” Production of crosslinked, hollow nanoparticles by surface-initiated living free-radical polymerizatio”n Journal of Polymer Science Part A-Polymer Chemistry, 2002, 40, 1309.
  42. Harth, E.; Hecht, S.; Helms, B.A.; Malmstrom, E.E.; Fréchet, J.M.J.; Hawker, C.J. “The effect of macromolecular architecture in nanomaterials: A comparison of site isolation in phorphyrin core dendrimers and their isomeric linear analogs.” Journal of the American Chemical Society, 2002, 124, 3926.
  43. Hawker, C.J.; Bosman, A.W.; Harth, E.; “New polymer synthesis by nitroxide mediated living radical polymerizations.”Chemical Reviews, 2001, 101, 3661.
  44. Harth, E.; Bosman, A.W.; Benoit, D.; Helms, B.;  Fréchet, J.M.J.; Hawker, C.J. “A practical approach to the living polymerization of functional monomers: Application to block copolymers and 3-dimensional macromolecular architectures.”Macromolecular Symposium 2001, 174, 85.
  45. Harth, E.; Hawker, C.J.; Fan, W.; Waymouth, R.M. “Chain end functionalization in nitroxide-mediated free radical polymerizations.” Macromolecules. 2001, 34, 3856.
  46. Harth, E.; Van Horn, B.; Hawker, C.J. “Acceleration in nitroxide mediated ‘living’ free radical polymerizations.” Chemical Communications. 2001, 9, 823.
  47. Rodlert, M.; Harth, E.; Rees, I.; Hawker, C.J. “End-group fidelity in nitroxide-mediated living free radical polymerizations”Journal of Polymer Science Part A-Polymer Chemistry, 2000, 38, 4749.
  48. Benoit, D.; Harth, E.; Fox, P.; Waymouth R.M.; Hawker C.J. “Accurate structural control and block formation in the living polymerization of 1,3-dienes by nitroxide-mediated procedures” Macromolecules, 2000, 33, 363.
  49. Schubert, U.S.; Weidl, C.H.; Cattani, C.; Eschbaumer, C.; Newcome, G.R.; He, E.; Harth, E.; Mullen, K.; “Metallosupramolecular-fullerene assemblies and polymers”, Polym. Prep, 2000, 41(1), 229.
  50. Schubert, U.S.; Weidl, C.H.; Rapta, P.; Harth, E.; Mullen, K.; “Metallo-supramolecular fullerene architectures: Synthesis and characterization of bucky ligands and a non-covalent dimer.” Chemistry Letters, 1999, 9, 949.
  51. Kallinger, C.; Hauder, M.; Haugeneder, A.; Lemmer, U.; Spirkl, W.; Feldmann, J.; Scherf, U.; Harth, E.; Gugel, A.; Mullen, K. “Control of electron transfer in conjugated polymer fullerene heterostructures” Synthetic Metals, 1999, 101(1-3), 285.
  52. Hong, H.; Davidov, D.; Kallinger, C.; Lemmer, U.; Feldmann, J.; Harth, E.; Gugel, A.; Mullen, K. “Self-assembly of functionalized fullerenes.” Synthetic Metals, 1999, 102(1-3), 1487.
  53. Haugeneder, A.; Neges, M.; Kallinger, C.; Spirkl, W.; Lemmer, U.; Feldmann, J.; Scherf, U.; Harth, E.; Gugel, A.; Mullen, K. “Exiton diffusion and dissociation in conjugated fullerene blends and heterostructures.” Physical Review B-Condensed Matter 1999, 59 (23), 15346.
  54. Kocher, M.; Daubler, T.K.; Harth, E.; Scherf, U.; Gugel, A.; Neher, D. “Photoconductivity of an inorganic/organic composite containing dye-sensitized nanocrystalline titanium dioxide.” Applied Physical Letters, 1998, 72(6), 650.
  55. Kallinger,C.; Haugeneder, A.; Lemmer, U.; Feldmann, J.; Hong H.; Tarabia, M.; Daviov, D.; Harth, E.; Walter, M.; Scherf, U.; Gugel, A.; Mullen, K., in Molecular Nanostructures, edited by Kuzmany, H.; Fink, J.; Mehring, M.; Roth, S.; (World Scientific, Singnapore, 1997), 515.
  56. Gugel, A.; Belik, P.; Walter, M.; Kraus, A.; Harth, E.; Wagner, M.; Spickermann, J.; Mullen, K. “The repetitive Diels-Alder reaction: A new approach to [60]fullerene main-chain polymers.” Tetrahedron 1996, 52(14), 5007.
  57. Jonas, U.; Cardullo, F.; Belik, P.; Diederich F.; Gugel, A.; Harth, E.; Herrmann, A.; Isaacs, L.; Mullen, K.; Ringsdorf, H.; Thilgen, C.; Uhlmann, P.; Vasella, A.; Waldraff, C.A.A.; Walter, M. “Synthesis of a fullerene[60] cryptate and systematic Langmuir-Blodgett and thin-film investigations of amphiphilic fullerene derivatives.” Chemistry-A European Journal, 1995, 1(4), 243.
  58. Uhlmann, P.; Harth, E.; Naughton, A.B.; Vasella A. “Glycosylidene carbenes 20: Synthesis of deprotected, spiro-linked C-Glycosides of C-60.” Helvetica Chimica Acta 1994, 77(8), 2335.